Are temp files and invalid entries destructive for your system and how can I clean it?

Yes temp files and invalid entries r destructive for your system .These corrupted files can be removed just by using registry cleaner.

These files are not destructive, just unnecessary.
Use CCleaner to remove temp files, avoid any and all registry cleaners as they are often wrong, and may damage your system.
http://www.ccleaner.com/

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