EdWeb 0 Newbie Poster

Having numerous issues here. Windows Defender cannot update, getting various error codes each time I try. Such as 0x80040154 and 0x8007043c. Have tried various solution suggestions on Internet but none work.
Also, Internet Explorer will not load Windows Updates and cannot load Microsoft Update engine. Tried in safe mode also.
Also, when using Search Companion to look for files and folders, all panels are blank.

Here is the Hijack log for my machine. Any help much appreciated.

Logfile of HijackThis v1.99.1
Scan saved at 1:10:15 PM, on 6/28/2007
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\System32\ibmpmsvc.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\Windows Defender\MsMpEng.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\System32\S24EvMon.exe
C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
C:\Program Files\Common Files\Symantec Shared\ccSetMgr.exe
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\system32\bmwebcfg.exe
C:\PROGRA~1\NETSUP~1\client32.exe
C:\Program Files\Cisco Systems\VPN Client\cvpnd.exe
C:\Program Files\Symantec AntiVirus\DefWatch.exe
C:\WINDOWS\System32\svchost.exe
C:\WINDOWS\system32\cba\pds.exe
C:\PROGRA~1\Symantec\SYMANT~1\NSCTOP.EXE
C:\WINDOWS\System32\QCONSVC.EXE
C:\WINDOWS\System32\RegSrvc.exe
C:\Program Files\Symantec AntiVirus\SavRoam.exe
C:\Program Files\Analog Devices\SoundMAX\SMAgent.exe
C:\Program Files\Microsoft SQL Server\90\Shared\sqlwriter.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Symantec AntiVirus\Rtvscan.exe
C:\WINDOWS\system32\TpKmpSVC.exe
C:\PROGRA~1\Xpoint\xpadmin\xpadmin.exe
C:\PROGRA~1\Xpoint\agent\Xpagent.exe
C:\WINDOWS\system32\ams_ii\hndlrsvc.exe
C:\WINDOWS\system32\MsgSys.EXE
C:\WINDOWS\system32\ams_ii\iao.exe
C:\WINDOWS\system32\cba\xfr.exe
C:\PROGRA~1\Xpoint\EEClient\xpclient.exe
C:\WINDOWS\system32\cmd.exe
C:\PROGRA~1\Xpoint\SAS\jre\bin\javaw.exe
C:\Program Files\Citrix\ICA Client\ssonsvr.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\TpShocks.exe
C:\PROGRA~1\ThinkPad\PkgMgr\HOTKEY\TPHKMGR.exe
C:\Program Files\Synaptics\SynTP\SynTPLpr.exe
C:\Program Files\Synaptics\SynTP\SynTPEnh.exe
C:\Program Files\Xpoint\PE\Skin\rrpcsb.exe
C:\Program Files\QuickTime\qttask.exe
C:\Program Files\ThinkPad\ConnectUtilities\QCWLICON.EXE
C:\Program Files\Xpoint\PE\pcrecsa.exe
C:\PROGRA~1\ThinkPad\CONNEC~1\QCTray.exe
C:\Program Files\Intel\NCS\PROSet\PRONoMgr.exe
C:\Program Files\ThinkPad\PkgMgr\HOTKEY\TPONSCR.exe
C:\Program Files\ThinkPad\PkgMgr\HOTKEY_1\TpScrex.exe
C:\Program Files\Musicmatch\Musicmatch Jukebox\mm_tray.exe
C:\Program Files\Common Files\InstallShield\UpdateService\issch.exe
C:\PROGRA~1\MUSICM~1\MUSICM~1\MMDiag.exe
C:\PROGRA~1\ThinkPad\UTILIT~1\EzEjMnAp.Exe
C:\WINDOWS\AGRSMMSG.exe
C:\WINDOWS\system32\dla\tfswctrl.exe
C:\WINDOWS\system32\RunDll32.exe
C:\Program Files\Common Files\Symantec Shared\ccApp.exe
C:\PROGRA~1\SYMANT~1\VPTray.exe
C:\Program Files\Musicmatch\Musicmatch Jukebox\mim.exe
C:\Program Files\Windows Defender\MSASCui.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Adobe\Acrobat 5.0\Distillr\AcroTray.exe
C:\Program Files\ArcSoft\Media Card Companion\MCC Monitor.exe
C:\Program Files\OpenOffice.org 2.1\program\soffice.exe
C:\Program Files\OpenOffice.org 2.1\program\soffice.BIN
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\ViewApps\ViewMail\ViewMail.exe
C:\Program Files\Common Files\Voice Mail Client\AVRPCHelper.EXE
C:\Program Files\Citrix\ICA Client\pn.exe
C:\PROGRA~1\Citrix\ICACLI~1\Wfcrun32.exe
C:\PROGRA~1\Citrix\ICACLI~1\WFICA32.EXE
C:\PROGRA~1\MICROS~2\OFFICE11\OUTLOOK.EXE
C:\Program Files\Microsoft Office\OFFICE11\WINWORD.EXE
C:\Program Files\Internet Explorer\iexplore.exe
C:\Program Files\NetSupport Manager\PCICTLUI.EXE
C:\WINDOWS\system32\NOTEPAD.EXE
C:\Downloads\HiJack\HijackThis.exe

R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://securityresponse.symantec.com/avcenter/fix_homepage
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant = about:blank
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = prlisa2.ads.integratelecom.com:8080
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = www.sms800gui.com;10.*;192.168.*;*.ads.integratelecom.com;*qwestdexlive.com;216.60.102.*;216.60.102.*;*dexpages.com;<local>
O2 - BHO: HelperObject Class - {00C6482D-C502-44C8-8409-FCE54AD9C208} - C:\Program Files\TechSmith\SnagIt 7\SnagItBHO.dll
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Adobe\Acrobat 7.0\ActiveX\AcroIEHelper.dll
O2 - BHO: (no name) - {53707962-6F74-2D53-2644-206D7942484F} - C:\Program Files\Spybot - Search & Destroy\SDHelper.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.5.0_06\bin\ssv.dll
O2 - BHO: BrowserHelper Class - {EBCDDA60-2A68-11D3-8A43-0060083CFB9C} - C:\WINDOWS\system32\nzdd.dll
O3 - Toolbar: SnagIt - {8FF5E183-ABDE-46EB-B09E-D2AAB95CABE3} - C:\Program Files\TechSmith\SnagIt 7\SnagItIEAddin.dll
O4 - HKLM\..\Run: [ATIPTA] C:\Program Files\ATI Technologies\ATI Control Panel\atiptaxx.exe
O4 - HKLM\..\Run: [UserFaultCheck] %systemroot%\system32\dumprep 0 -u
O4 - HKLM\..\Run: [UC_Start] C:\IBMTools\Updater\ucstartup.exe
O4 - HKLM\..\Run: [TpShocks] TpShocks.exe
O4 - HKLM\..\Run: [TPKMAPHELPER] C:\Program Files\ThinkPad\Utilities\TpKmapAp.exe -helper
O4 - HKLM\..\Run: [TPHOTKEY] C:\PROGRA~1\ThinkPad\PkgMgr\HOTKEY\TPHKMGR.exe
O4 - HKLM\..\Run: [TP4EX] tp4ex.exe
O4 - HKLM\..\Run: [SynTPLpr] C:\Program Files\Synaptics\SynTP\SynTPLpr.exe
O4 - HKLM\..\Run: [SynTPEnh] C:\Program Files\Synaptics\SynTP\SynTPEnh.exe
O4 - HKLM\..\Run: [Synchronization Manager] %SystemRoot%\system32\mobsync.exe /logon
O4 - HKLM\..\Run: [S3TRAY2] S3Tray2.exe
O4 - HKLM\..\Run: [Rapid Restore] C:\Program Files\Xpoint\PE\Skin\rrpcsb.exe
O4 - HKLM\..\Run: [QuickTime Task] "C:\Program Files\QuickTime\qttask.exe" -atboottime
O4 - HKLM\..\Run: [QCWLICON] C:\Program Files\ThinkPad\ConnectUtilities\QCWLICON.EXE
O4 - HKLM\..\Run: [QCTray] C:\PROGRA~1\ThinkPad\CONNEC~1\QCTray.exe
O4 - HKLM\..\Run: [PRONoMgr.exe] C:\Program Files\Intel\NCS\PROSet\PRONoMgr.exe
O4 - HKLM\..\Run: [NeroFilterCheck] C:\WINDOWS\system32\NeroCheck.exe
O4 - HKLM\..\Run: [MMTray] "C:\Program Files\Musicmatch\Musicmatch Jukebox\mm_tray.exe"
O4 - HKLM\..\Run: [MimBoot] C:\PROGRA~1\MUSICM~1\MUSICM~1\mimboot.exe
O4 - HKLM\..\Run: [ISUSScheduler] "C:\Program Files\Common Files\InstallShield\UpdateService\issch.exe" -start
O4 - HKLM\..\Run: [ISUSPM Startup] C:\PROGRA~1\COMMON~1\INSTAL~1\UPDATE~1\ISUSPM.exe -startup
O4 - HKLM\..\Run: [EZEJMNAP] C:\PROGRA~1\ThinkPad\UTILIT~1\EzEjMnAp.Exe
O4 - HKLM\..\Run: [BMMLREF] C:\Program Files\ThinkPad\Utilities\BMMLREF.EXE
O4 - HKLM\..\Run: [BluetoothAuthenticationAgent] rundll32.exe irprops.cpl,,BluetoothAuthenticationAgent
O4 - HKLM\..\Run: [AGRSMMSG] AGRSMMSG.exe
O4 - HKLM\..\Run: [dla] C:\WINDOWS\system32\dla\tfswctrl.exe
O4 - HKLM\..\Run: [BMMGAG] RunDll32 C:\PROGRA~1\ThinkPad\UTILIT~1\pwrmonit.dll,StartPwrMonitor
O4 - HKLM\..\Run: [ccApp] "C:\Program Files\Common Files\Symantec Shared\ccApp.exe"
O4 - HKLM\..\Run: [vptray] C:\PROGRA~1\SYMANT~1\VPTray.exe
O4 - HKLM\..\Run: [Windows Defender] "C:\Program Files\Windows Defender\MSASCui.exe" -hide
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [NBJ] "C:\Program Files\Ahead\Nero BackItUp\NBJ.exe"
O4 - HKCU\..\Run: [MsnMsgr] "C:\Program Files\MSN Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe
O4 - Startup: OpenOffice.org 2.1.lnk = C:\Program Files\OpenOffice.org 2.1\program\quickstart.exe
O4 - Global Startup: Acrobat Assistant.lnk = C:\Program Files\Adobe\Acrobat 5.0\Distillr\AcroTray.exe
O4 - Global Startup: Adobe Reader Speed Launch.lnk = C:\Program Files\Adobe\Acrobat 7.0\Reader\reader_sl.exe
O4 - Global Startup: Monitor.lnk = C:\Program Files\ArcSoft\Media Card Companion\MCC Monitor.exe
O4 - Global Startup: RealDownload.lnk = C:\Program Files\Real\RealDownload\Realdownload.exe
O4 - Global Startup: VPN Client.lnk = ?
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_06\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.5.0_06\bin\ssv.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O11 - Options group: [JAVA_IBM] Java (IBM)
O12 - Plugin for .spop: C:\Program Files\Internet Explorer\Plugins\NPDocBox.dll
O16 - DPF: {02E09B2E-2A03-4572-9291-69900C068564} (LCSim Control) - http://www.learnitcorp.com/cabs/lcsim.cab
O16 - DPF: {0742B9EF-8C83-41CA-BFBA-830A59E23533} (Microsoft Data Collection Control) - https://support.microsoft.com/OAS/ActiveX/MSDcode.cab
O16 - DPF: {4531AB38-01E8-4A1C-B3A7-7CDFBDB02CE0} (DNA Helpdesk Remote Control Ax) - http://build1/helpdesk/rcax.cab
O16 - DPF: {6414512B-B978-451D-A0D8-FCFDF33E833C} (WUWebControl Class) - http://update.microsoft.com/windowsupdate/v6/V5Controls/en/x86/client/wuweb_site.cab?1134762224218
O16 - DPF: {6E32070A-766D-4EE6-879C-DC1FA91D2FC3} (MUWebControl Class) - http://update.microsoft.com/microsoftupdate/v6/V5Controls/en/x86/client/muweb_site.cab?1177628937466
O16 - DPF: {74D05D43-3236-11D4-BDCD-00C04F9A3B61} (HouseCall Control) - http://a840.g.akamai.net/7/840/537/2004061001/housecall.trendmicro.com/housecall/xscan53.cab
O16 - DPF: {74FFE28D-2378-11D5-990C-006094235084} (IBM Access Support) - http://www-307.ibm.com/pc/support/IbmEgath.cab
O16 - DPF: {76E5AF9D-2B3E-4FEB-A31F-A9E63A27FA29} (IASRunner Class) - https://www.ibm.com/pc/support/access/aslibmain/content/AcpIR.cab
O16 - DPF: {E598AC61-4C6F-4F4D-877F-FAC49CA91FA3} (acpRunner Class) - file://C:\Program Files\Support.com\Bin\IBMAccessSupport\common\install\AcpControl.cab
O17 - HKLM\System\CCS\Services\Tcpip\Parameters: Domain = ads.integratelecom.com
O17 - HKLM\Software\..\Telephony: DomainName = ads.integratelecom.com
O17 - HKLM\System\CS1\Services\Tcpip\Parameters: Domain = ads.integratelecom.com
O17 - HKLM\System\CS1\Services\Tcpip\Parameters: SearchList = ads.integratelecom.com,net.integratelecom.com
O17 - HKLM\System\CS2\Services\Tcpip\Parameters: Domain = ads.integratelecom.com
O17 - HKLM\System\CS2\Services\Tcpip\Parameters: SearchList = ads.integratelecom.com,net.integratelecom.com
O17 - HKLM\System\CCS\Services\Tcpip\Parameters: SearchList = ads.integratelecom.com,net.integratelecom.com
O18 - Protocol: ms-help - {314111C7-A502-11D2-BBCA-00C04F8EC294} - C:\Program Files\Common Files\Microsoft Shared\Help\hxds.dll
O20 - Winlogon Notify: NavLogon - C:\WINDOWS\system32\NavLogon.dll
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: Bytemobile Web Configurator (bmwebcfg) - Bytemobile, Inc. - C:\WINDOWS\system32\bmwebcfg.exe
O23 - Service: Symantec Event Manager (ccEvtMgr) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\ccEvtMgr.exe
O23 - Service: Symantec Settings Manager (ccSetMgr) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\ccSetMgr.exe
O23 - Service: Client32 - NetSupport Ltd - C:\PROGRA~1\NETSUP~1\client32.exe
O23 - Service: Cisco Systems, Inc. VPN Service (CVPND) - Cisco Systems, Inc. - C:\Program Files\Cisco Systems\VPN Client\cvpnd.exe
O23 - Service: Symantec AntiVirus Definition Watcher (DefWatch) - Symantec Corporation - C:\Program Files\Symantec AntiVirus\DefWatch.exe
O23 - Service: HP Web Jetadmin (HPWebJetadmin) - Unknown owner - C:\Program Files\HP Web Jetadmin\hpwebjetd.exe" -k runservice (file missing)
O23 - Service: IBM PM Service (IBMPMSVC) - Unknown owner - C:\WINDOWS\System32\ibmpmsvc.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: Intel Alert Handler - LANDesk Software Ltd. - C:\WINDOWS\system32\ams_ii\hndlrsvc.exe
O23 - Service: Intel Alert Originator - LANDesk Software Ltd. - C:\WINDOWS\system32\ams_ii\iao.exe
O23 - Service: Intel File Transfer - LANDesk Software Ltd. - C:\WINDOWS\system32\cba\xfr.exe
O23 - Service: Intel PDS - LANDesk Software Ltd. - C:\WINDOWS\system32\cba\pds.exe
O23 - Service: LiveUpdate - Symantec Corporation - C:\PROGRA~1\Symantec\LIVEUP~1\LUCOMS~1.EXE
O23 - Service: SQL Server (SQLEXPRESS) (MSSQL$SQLEXPRESS) - Unknown owner - C:\Program Files\Microsoft SQL Server\MSSQL.1\MSSQL\Binn\sqlservr.exe" -sSQLEXPRESS (file missing)
O23 - Service: Intel NCS NetService (NetSvc) - Intel(R) Corporation - C:\Program Files\Intel\NCS\Sync\NetSvc.exe
O23 - Service: Symantec System Center Discovery Service (NSCTOP) - Symantec Corporation - C:\PROGRA~1\Symantec\SYMANT~1\NSCTOP.EXE
O23 - Service: OracleClientCache80 - Unknown owner - C:\orant\BIN\ONRSD80.EXE
O23 - Service: Xpoint PCRadmin Server (PCRadminServer) - Unknown owner - C:\PROGRA~1\Xpoint\PE\pcradmin.exe
O23 - Service: Port Reporter (PortReporter) - Unknown owner - C:\Program Files\PortReporter\portreporter.exe
O23 - Service: IBM PSA Access Driver Control (PsaSrv) - Unknown owner - C:\WINDOWS\system32\PsaSrv.exe
O23 - Service: QCONSVC - IBM Corp. - C:\WINDOWS\System32\QCONSVC.EXE
O23 - Service: RegSrvc - Intel Corporation - C:\WINDOWS\System32\RegSrvc.exe
O23 - Service: Remote Packet Capture Protocol v.0 (experimental) (rpcapd) - Unknown owner - %ProgramFiles%\WinPcap\rpcapd.exe" -d -f "%ProgramFiles%\WinPcap\rpcapd.ini (file missing)
O23 - Service: Spectrum24 Event Monitor (S24EventMonitor) - Intel Corporation - C:\WINDOWS\System32\S24EvMon.exe
O23 - Service: SAVRoam (SavRoam) - symantec - C:\Program Files\Symantec AntiVirus\SavRoam.exe
O23 - Service: Symantec Network Drivers Service (SNDSrvc) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\SNDSrvc.exe
O23 - Service: SoundMAX Agent Service (SoundMAX Agent Service (default)) - Analog Devices, Inc. - C:\Program Files\Analog Devices\SoundMAX\SMAgent.exe
O23 - Service: Symantec SPBBCSvc (SPBBCSvc) - Symantec Corporation - C:\Program Files\Common Files\Symantec Shared\SPBBC\SPBBCSvc.exe
O23 - Service: Symantec AntiVirus - Symantec Corporation - C:\Program Files\Symantec AntiVirus\Rtvscan.exe
O23 - Service: IBM KCU Service (TpKmpSVC) - Unknown owner - C:\WINDOWS\system32\TpKmpSVC.exe
O23 - Service: SMS Remote Control Agent (Wuser32) - Unknown owner - C:\WINDOWS\system32\CCM\CLICOMP\RemCtrl\Wuser32.exe (file missing)
O23 - Service: Xpoint Admin Server (XPadminServer) - Unknown owner - C:\PROGRA~1\Xpoint\xpadmin\xpadmin.exe
O23 - Service: Xpoint Agent Server (xpAgentServer) - Unknown owner - C:\PROGRA~1\Xpoint\agent\Xpagent.exe