hey guys, my sister asked me to help her fix her laptop, I don't really know the full situation but she said she downloaded something and her laptop restarted in safe mode and thats all she could start it on. Shes running vista SP1. Here is the Hijack Log File, thanks for all your help in advanced !

Logfile of Trend Micro HijackThis v2.0.2
Scan saved at 6:07:00 PM, on 04/02/2009
Platform: Windows Vista SP1 (WinNT 6.00.1905)
MSIE: Internet Explorer v7.00 (7.00.6001.18000)
Boot mode: Safe mode

Running processes:
C:\Windows\Explorer.EXE
c:\PROGRA~1\mcafee.com\agent\mcagent.exe
C:\Program Files\McAfee\MSC\mcshell.exe
c:\PROGRA~1\mcafee\VIRUSS~1\mcvsshld.exe
C:\HJT\analysethis.exe

R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.sonystyle.ca/vaio
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKCU\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.hotmail.com/
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://go.microsoft.com/fwlink/?LinkId=69157
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://go.microsoft.com/fwlink/?LinkId=69157
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,SearchAssistant =
R0 - HKLM\Software\Microsoft\Internet Explorer\Search,CustomizeSearch =
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyServer = 64.59.144.95:8080
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R0 - HKCU\Software\Microsoft\Internet Explorer\Toolbar,LinksFolderName =
R3 - URLSearchHook: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\PROGRA~1\Yahoo!\Companion\Installs\cpn\yt.dll
O1 - Hosts: ::1 localhost
O2 - BHO: &Yahoo! Toolbar Helper - {02478D38-C3F9-4efb-9B51-7695ECA05670} - C:\PROGRA~1\Yahoo!\Companion\Installs\cpn\yt.dll
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0\bin\ssv.dll
O2 - BHO: scriptproxy - {7DB2D5A0-7241-4E79-B68D-6309F01C5231} - c:\PROGRA~1\mcafee\VIRUSS~1\scriptsn.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - C:\Program Files\Google\Google Toolbar\GoogleToolbar.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\5.0.926.3450\swg.dll
O2 - BHO: McAfee SiteAdvisor BHO - {B164E929-A1B6-4A06-B104-2CD0E90A88FF} - c:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O2 - BHO: Google Dictionary Compression sdch - {C84D72FE-E17D-4195-BB24-76C02E2E7C4E} - C:\Program Files\Google\Google Toolbar\Component\fastsearch_219B3E1547538286.dll
O3 - Toolbar: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - C:\PROGRA~1\Yahoo!\Companion\Installs\cpn\yt.dll
O3 - Toolbar: McAfee SiteAdvisor Toolbar - {0EBBBE48-BAD4-4B4C-8E5A-516ABECAE064} - c:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O3 - Toolbar: &Google Toolbar - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - C:\Program Files\Google\Google Toolbar\GoogleToolbar.dll
O4 - HKLM\..\Run: [Windows Defender] %ProgramFiles%\Windows Defender\MSASCui.exe -hide
O4 - HKLM\..\Run: [HotKeysCmds] C:\Windows\system32\hkcmd.exe
O4 - HKLM\..\Run: [Persistence] C:\Windows\system32\igfxpers.exe
O4 - HKLM\..\Run: [RtHDVCpl] RtHDVCpl.exe
O4 - HKLM\..\Run: [Apoint] C:\Program Files\Apoint\Apoint.exe
O4 - HKLM\..\Run: [ISBMgr.exe] "C:\Program Files\Sony\ISB Utility\ISBMgr.exe"
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0\bin\jusched.exe"
O4 - HKLM\..\Run: [iTunesHelper] "C:\Program Files\iTunes\iTunesHelper.exe"
O4 - HKLM\..\Run: [snpstd] C:\Windows\vsnpstd.exe
O4 - HKLM\..\Run: [NeroFilterCheck] C:\Program Files\Common Files\Ahead\Lib\NeroCheck.exe
O4 - HKLM\..\Run: [mcagent_exe] "C:\Program Files\McAfee.com\Agent\mcagent.exe" /runkey
O4 - HKCU\..\Run: [Sidebar] C:\Program Files\Windows Sidebar\sidebar.exe /autoRun
O4 - HKCU\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter
O4 - HKCU\..\Run: [Messenger (Yahoo!)] "C:\Program Files\Yahoo!\Messenger\YahooMessenger.exe" -quiet
O4 - HKCU\..\Run: [MsnMsgr] "C:\Program Files\Windows Live\Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [WMPNSCFG] C:\Program Files\Windows Media Player\WMPNSCFG.exe
O4 - HKCU\..\Run: [LightScribe Control Panel] C:\Program Files\Common Files\LightScribe\LightScribeControlPanel.exe -hidden
O4 - HKCU\..\Run: [swg] C:\Program Files\Google\GoogleToolbarNotifier\GoogleToolbarNotifier.exe
O4 - HKCU\..\RunOnce: [FlashPlayerUpdate] C:\Windows\system32\Macromed\Flash\FlashUtil9f.exe
O4 - HKUS\S-1-5-19\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-19\..\Run: [WindowsWelcomeCenter] rundll32.exe oobefldr.dll,ShowWelcomeCenter (User 'LOCAL SERVICE')
O4 - HKUS\S-1-5-20\..\Run: [Sidebar] %ProgramFiles%\Windows Sidebar\Sidebar.exe /detectMem (User 'NETWORK SERVICE')
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~3\Office12\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0\bin\npjpi160.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0\bin\npjpi160.dll
O9 - Extra button: Send to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~3\Office12\ONBttnIE.dll
O9 - Extra 'Tools' menuitem: S&end to OneNote - {2670000A-7350-4f3c-8081-5663EE0C6C49} - C:\PROGRA~1\MICROS~3\Office12\ONBttnIE.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~3\Office12\REFIEBAR.DLL
O13 - Gopher Prefix:
O16 - DPF: {30528230-99f7-4bb4-88d8-fa1d4f56a2ab} (YInstStarter Class) - C:\Program Files\Yahoo!\Common\yinsthelper.dll
O17 - HKLM\System\CCS\Services\Tcpip\..\{18679724-6529-4EC5-9F43-C487B9B6A19A}: NameServer = 85.255.112.39,85.255.112.40
O17 - HKLM\System\CCS\Services\Tcpip\..\{8536FC0A-9696-4C16-8774-4DA2E0D334AF}: NameServer = 85.255.112.39,85.255.112.40
O17 - HKLM\System\CS1\Services\Tcpip\Parameters: NameServer = 85.255.112.39,85.255.112.40
O17 - HKLM\System\CS1\Services\Tcpip\..\{18679724-6529-4EC5-9F43-C487B9B6A19A}: NameServer = 85.255.112.39,85.255.112.40
O17 - HKLM\System\CCS\Services\Tcpip\Parameters: NameServer = 85.255.112.39,85.255.112.40
O18 - Protocol: sacore - {5513F07E-936B-4E52-9B00-067394E91CC5} - c:\PROGRA~1\mcafee\SITEAD~1\mcieplg.dll
O23 - Service: Adobe Active File Monitor V6 (AdobeActiveFileMonitor6.0) - Unknown owner - C:\Program Files\Adobe\Photoshop Elements 6.0\PhotoshopElementsFileAgent.exe
O23 - Service: Apple Mobile Device - Apple Inc. - C:\Program Files\Common Files\Apple\Mobile Device Support\bin\AppleMobileDeviceService.exe
O23 - Service: Bonjour Service - Apple Inc. - C:\Program Files\Bonjour\mDNSResponder.exe
O23 - Service: FLEXnet Licensing Service - Macrovision Europe Ltd. - C:\Program Files\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: Google Updater Service (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: IviRegMgr - InterVideo - C:\Program Files\Common Files\InterVideo\RegMgr\iviRegMgr.exe
O23 - Service: LightScribeService Direct Disc Labeling Service (LightScribeService) - Hewlett-Packard Company - C:\Program Files\Common Files\LightScribe\LSSrvc.exe
O23 - Service: McAfee SiteAdvisor Service - Unknown owner - C:\Program Files\McAfee\SiteAdvisor\McSACore.exe
O23 - Service: McAfee Services (mcmscsvc) - McAfee, Inc. - C:\PROGRA~1\McAfee\MSC\mcmscsvc.exe
O23 - Service: McAfee Network Agent (McNASvc) - McAfee, Inc. - c:\program files\common files\mcafee\mna\mcnasvc.exe
O23 - Service: McAfee Scanner (McODS) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcods.exe
O23 - Service: McAfee Proxy Service (McProxy) - McAfee, Inc. - c:\PROGRA~1\COMMON~1\mcafee\mcproxy\mcproxy.exe
O23 - Service: McAfee Real-time Scanner (McShield) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcshield.exe
O23 - Service: McAfee SystemGuards (McSysmon) - McAfee, Inc. - C:\PROGRA~1\McAfee\VIRUSS~1\mcsysmon.exe
O23 - Service: McAfee Personal Firewall Service (MpfService) - McAfee, Inc. - C:\Program Files\McAfee\MPF\MPFSrv.exe
O23 - Service: MSCSPTISRV - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\MSCSPTISRV.exe
O23 - Service: NBService - Nero AG - C:\Program Files\Nero\Nero 7\Nero BackItUp\NBService.exe
O23 - Service: NMIndexingService - Nero AG - C:\Program Files\Common Files\Ahead\Lib\NMIndexingService.exe
O23 - Service: PACSPTISVR - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\PACSPTISVR.exe
O23 - Service: ProtexisLicensing - Unknown owner - C:\Windows\system32\PSIService.exe
O23 - Service: VAIO Media plus Content Importer (SOHCImp) - Sony Corporation - C:\Program Files\Sony\VAIO Media plus\SOHCImp.exe
O23 - Service: VAIO Media plus Digital Media Server (SOHDms) - Sony Corporation - C:\Program Files\Sony\VAIO Media plus\SOHDms.exe
O23 - Service: VAIO Media plus Device Searcher (SOHDs) - Sony Corporation - C:\Program Files\Sony\VAIO Media plus\SOHDs.exe
O23 - Service: Sony SPTI Service (SPTISRV) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\AVLib\SPTISRV.exe
O23 - Service: VAIO Entertainment TV Device Arbitration Service - Sony Corporation - C:\Program Files\Common Files\Sony Shared\VAIO Entertainment Platform\VzCs\VzHardwareResourceManager\VzHardwareResourceManager.exe
O23 - Service: VAIO Event Service - Sony Corporation - C:\Program Files\Sony\VAIO Event Service\VESMgr.exe
O23 - Service: VAIO Content Metadata Intelligent Analyzing Manager (VcmIAlzMgr) - Sony Corporation - C:\Program Files\Sony\VCM Intelligent Analyzing Manager\VcmIAlzMgr.exe
O23 - Service: VAIO Content Metadata XML Interface (VcmXmlIfHelper) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\VcmXml\VcmXmlIfHelper.exe
O23 - Service: VAIO Entertainment UPnP Client Adapter (Vcsw) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\VAIO Entertainment Platform\VCSW\VCSW.exe
O23 - Service: VAIO Entertainment Database Service (VzCdbSvc) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\VAIO Entertainment Platform\VzCdb\VzCdbSvc.exe
O23 - Service: VAIO Entertainment File Import Service (VzFw) - Sony Corporation - C:\Program Files\Common Files\Sony Shared\VAIO Entertainment Platform\VzCdb\VzFw.exe
O23 - Service: XAudioService - Conexant Systems, Inc. - C:\Windows\system32\DRIVERS\xaudio.exe

--
End of file - 10929 bytes

i just rebooted her computer, up until the login screen everythiong was working fine and the blue screen of death popped up and it rebooted itself and when it loaded it asked how i wanted to boot it up, i guess this is why my sister could only boot it up on safe mode.

There is a nasty infection on board.

Download Malwarebytes' Anti-Malware (http://www.majorgeeks.com/Malwarebytes_Anti-Malware_d5756.html) to your desktop.

* Double-click mbam-setup.exe and follow the prompts to install the program.
* At the end, be sure to checkmark the Update Malwarebytes' Anti-Malware and Launch Malwarebytes' Anti-Malware, then click Finish.
* If an update is found, it will download and install the latest version.
* Once the program has loaded, select Perform full scan, then click Scan.
* When the scan is complete, click OK, then Show Results to view the results.
* Be sure that everything is checked, and click Remove Selected.
* When completed, a log will open in Notepad.
* Post the log back here.

Make sure that you restart the computer.

The log can also be found here:
C:\Documents and Settings\Username\Application Data\Malwarebytes\Malwarebytes' Anti-Malware\Logs\log-date.txt
Or at C:\Program Files\Malwarebytes' Anti-Malware\Logs\log-date.txt

Post new HJT log.

theres a problem with that crunchie, i can only boot the laptop on safe mode so i have no access to the internet whatsoever, so i can't update malware bytes.

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